Lasagna is the ultimate comfort food—but when you replace the traditional tomato sauce with rich, velvety Alfredo and add tender chicken, you elevate it to a whole new level of indulgence. This Alfredo Chicken Lasagna is the perfect dish for special dinners, cozy gatherings, or any time you crave something creamy, cheesy, and soul-satisfying.

This isn’t your average lasagna. With layers of ricotta, melty mozzarella, savory chicken, and a luscious Alfredo cream sauce, each bite is a creamy, flavor-packed experience. This recipe is simple enough for weeknights yet impressive enough for entertaining guests.

Who Will Love This Recipe?

This lasagna is ideal for:

• Cream sauce lovers who want something beyond the usual red sauce.

• Busy families looking for a filling and delicious meal that can be prepped in advance.

• Entertainers seeking a crowd-pleasing main course that looks as good as it tastes.

• Anyone craving the cozy comfort of homemade lasagna with a luxurious twist.

If you’re tired of traditional red sauce lasagna and want something more elegant and creamy, this one’s for you.

Ingredients for Alfredo Chicken Lasagna

Here’s everything you need to create this irresistible dish:

• 12 lasagna noodles

• 2 cups cooked chicken breast, shredded

• 2 cups ricotta cheese

• 2 cups shredded mozzarella cheese

• 1 cup grated Parmesan cheese

• 1 jar (16 oz) Alfredo sauce

• 1/2 cup heavy cream

• 1 tablespoon olive oil

• 1 small onion, chopped

• 2 cloves garlic, minced

• 1/2 teaspoon dried basil

• 1/4 teaspoon black pepper

• 1/4 teaspoon salt

• Fresh parsley, chopped (for garnish)

Tip: Rotisserie chicken works beautifully here for convenience and extra flavor.

Step-by-Step Instructions

1. Prep the Oven and Noodles

Preheat your oven to 375°F (190°C). Boil the lasagna noodles according to package instructions. Once cooked, drain and set aside.

2. Cook the Aromatics

In a large skillet, heat olive oil over medium heat. Add the onion and garlic, sautéing for 2–3 minutes until softened and aromatic.

3. Add Chicken and Sauce

Stir in the shredded chicken, Alfredo sauce, heavy cream, basil, salt, and pepper. Allow the mixture to simmer gently for 5–7 minutes, letting the flavors meld into a creamy, savory sauce.

4. Make the Cheese Filling

In a mixing bowl, combine:

• Ricotta cheese

• 1 cup shredded mozzarella

• 1/2 cup Parmesan cheese

Mix well until fully combined and creamy.

5. Assemble the Lasagna

In a 9×13-inch baking dish, start with a thin layer of the chicken Alfredo sauce. Layer as follows:

1. Lasagna noodles

2. Ricotta cheese mixture

3. Chicken Alfredo sauce

Repeat layers until the dish is full, finishing with a layer of the ricotta mixture.

Sprinkle the remaining mozzarella and Parmesan cheese generously over the top.

6. Bake to Perfection

Cover the dish with aluminum foil and bake for 25 minutes. Then remove the foil and bake for another 10–15 minutes, or until the top is bubbly and golden brown.

Let the lasagna rest for 5 minutes before slicing to help it set.

7. Garnish and Serve

Top with freshly chopped parsley for a pop of color and freshness. Serve warm and enjoy every rich, creamy bite!

Kitchen Equipment Needed

To make this recipe, you’ll need:

• Large skillet

• Saucepan (for noodles)

• 9×13-inch baking dish

• Mixing bowls

• Wooden spoon or spatula

• Aluminum foil

• Cheese grater (if using fresh cheeses)

Storage and Reheating Tips

Leftovers? Lucky you! Here’s how to store and reheat this dish:

• Refrigerator: Store in an airtight container for up to 4 days.

• Freezer: Wrap portions tightly in foil and store in a freezer-safe container for up to 2 months.

• Reheat: Warm in the oven at 350°F for 15–20 minutes or microwave individual portions for 2–3 minutes.

Pro Tip: If reheating from frozen, allow to thaw overnight in the fridge for best results.

Recipe Swaps and Variations

Want to customize this dish to suit your taste or pantry?

• Vegetarian Version: Replace chicken with sautéed mushrooms, spinach, or roasted vegetables.

• Spicy Kick: Add a pinch of red pepper flakes to the Alfredo sauce.

• Pesto Twist: Swirl in 2 tablespoons of pesto with the Alfredo sauce for a herbaceous upgrade.

• Cheese Swap: Substitute ricotta with cottage cheese for a lighter version or use fontina for a more buttery melt.

Serving and Pairing Suggestions

This creamy lasagna pairs beautifully with:

• Garlic bread or toasted focaccia

• Steamed green beans, asparagus, or a crisp arugula salad

• White wine, such as Chardonnay or Pinot Grigio

• Sparkling water with lemon for a refreshing contrast

Frequently Asked Questions

Can I make this lasagna ahead of time?

Yes! Assemble it up to a day in advance and refrigerate it before baking. You can also freeze the unbaked lasagna and bake it from frozen — just add 15–20 minutes to the cooking time.

Do I have to use jarred Alfredo sauce?

No, you can make your own with butter, cream, garlic, and Parmesan. But jarred sauce works great for convenience and still tastes delicious.

Can I use no-boil noodles?

Yes! Just ensure there’s enough sauce to keep them moist during baking. Cover tightly with foil during the first bake to retain moisture.

What’s the best way to shred chicken?

Use two forks to pull apart cooked chicken breasts or pulse briefly in a food processor for a finer texture.

Final Thoughts

This Alfredo Chicken Lasagna is pure creamy, cheesy comfort food heaven. It’s a crowd-pleaser that blends classic lasagna with the smooth indulgence of Alfredo sauce and tender chicken, offering a delicious twist on tradition.

It’s ideal for feeding a family, meal prepping, or impressing dinner guests. The best part? It’s surprisingly easy to make, and leftovers are just as amazing (if not better!).

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